Aplasia medular en Argentina. 78 likes. Pagina en construcción. Niño, 9 años, con aplasia medular y trasplante de Hombre, 12 años, aplasia medular diagnosticada a los 8 disponentes como crisis hipertensiva severa, hi- . Eventualmente se llega a una aplasia medular severa en la mayoría de los casos, sin embargo la expresión completa de la pancitopenia es variable y puede.
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Autoimmune processes affecting the kidneys are heterogeneous clinical entities and their differential diagnosis is complex. The best example is systemic lupus erythematosus SLEwhose pleomorphisms can range from skin or joint lesions to lupus nephritis LN.
In this context, we present the case of a 40 year old patient with a history of smoking, obesity and high blood pressure HBP with no pharmacological treatment.
In light of these results, and suspecting a glomerular process, with incomplete data suggesting haemolytic anaemia, we performed zevera haemodialysis and a blood transfusion.
Advances in the treatment of aplastic anemia
Other results gathered at the same time were as follows: There were also signs of proliferative arteriopathy having to do with HBP Figure Tests found the following results: Anticardiolipin and lupus anticoagulant antibodies were negative. In addition, we also decided to administer granulocyte colony-stimulating factors filgrastim: However, there was no megakaryocyte response, and a bone marrow biopsy revealed intense hypoplasia with developmental anomalies, and glycophorin-negative proerythroblasts which might be linked to SLE, although it was impossible to rule out simultaneous chronic infection with parvovirus B19 Figure 2.
This association did not provide any haematological benefits and was manifestly unable to prevent a new episode of bloody diarrhoea complicated by a pulmonary haemorrhage which could not be resolved even by using combined treatment with daily dialysis and plasmapheresis.
In the end, the patient died in the intensive care unit due to sepsis secondary to infection with Escherichia coli.
Translation of “aplasia medular” in English
In conclusion, the case described is an excellent example of atypical SLE with severe LN aplasix no classical signs of the disease such as skin and joint disorders, with wasting syndrome fever, anaemia and severe renal failure being predominant. This fact, combined with the array of symptoms caused by CMV enteritis and pulmonary haemorrhage defined the final outcome and made us re-consider that both infections were co-existing opportunistic entities, and perhaps, the agents triggering the lupus flare.
The authors affirm that they have no conflicts of interest related to the content of this article. Severe glomerulosclerosis and tubular lesion.
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Nefrologia English Version ; Universidad de Granada, Granada. To the Editor, Autoimmune processes affecting the kidneys are heterogeneous clinical entities and their differential diagnosis is complex.
In light of these results, and suspecting a glomerular process, with incomplete data suggesting haemolytic anaemia, we performed aplasix haemodialysis and a blood transfusion. There were also signs of proliferative arteriopathy having to do with HBP Figure 1. In the end, the patient died in the intensive care unit due to sepsis secondary to infection with Escherichia coli.